Duragesic label page 1 full prescribing information for use. Many drugs interact with duragesic fentanyl transdermal patch and can raise the chance of side effects like deadly breathing problems. Fentanyl patches should only be used to treat longterm chronic pain by people who have previously taken high doses of prescription pain medicine opioids for 7 or more days without relief. The fentanyl patch, also called the duragesic patch, is a prescription skin patch containing strong pain medication for treating moderate to severe chronic pain. High doses of fentanyl can cause breathing to stop, leading to death. A certain amount of the medicine must build up in the skin before it is absorbed into the body. Duragesic fentanyl transdermal system for transdermal administration is an opioid analgesic. Fentanyl transdermal patch is available as a generic drug and as a brandname drug. Opioids are narcotics and include drugs like morphine, oxycondone oxycontin, and hydromorphone dilaudid. Because of this serious risk, fentanyl patches should only be used to treat people who are tolerant used to the effects of the medication to opioid medications. Duragesic fentanyl transdermal system is available in generic form. Remove the skin patch and call your doctor at once if you have.
Austin, texas vocus december, 2008 the law firm of hissey kientz, llp wishes to alert patients who use the duragesic fentanyl pain patch of the serious and potentially fatal health risks they may face from the use of this powerful painkilling drug the duragesic pain patch was first approved by the food and drug administration in august 1990 to treat certain patients with chronic pain. Fentanyl pain patch is dangerous online lawyer source. Jul 15, 2005 july 15, 2005 the fda today has issued a health advisory regarding the safe use of fentanyl skin patches brand name duragesic in response to reports of deaths in patients using this potent. Fentanyl pain patches lawsuits duragesic alert by health. My question pertains to combining transdermal fentanyl duragesic patch with either methadone or other shortacting opioids for breakthrough pain, cancerous or noncancerous. It has a rapid onset and its effects generally last less than two hours. However, it is important that people who used a fentanyl patch should know the signs of fentanyl overdose, which include slow heartbeat, slow breathing, pinpoint pupils, fainting, clammy skin, and seizures. Fentanyl transdermal interactions with other medication. A strong prescription pain medicine that contains an opioid narcotic that is used tomanage pain severe enough to require daily aroundtheclock, longterm treatment with an opioid,in people who are already regularly using. Duragesic is a skin patch containing fentanyl, an opioid pain medication. Fentanyl has a risk for abuse and addiction, which can lead to overdose and death. Patients who use duragesic or generic fentanyl patches need to be aware of the health dangers that could result from the use of these products.
Fentanyl duragesic patches come in six different sizes and doses, including. This may cause serious problems, including overdose and death. Some of the dosage forms listed on this page may not apply to the brand name duragesic in summary. Fentanyl patches provide a strong, effective, and continuous dose of pain medicine that helps prevent the pain peaks and valleys that come with other types of pain drugs. Duragesic transdermal patch 72 hour drug information. Serious and potentially fatal problems have been associated with the fentanyl pain patch fentanyl transdermal. Jun 19, 2019 duragesic is the most recognized brand name for fentanyl patches. Using damaged or cut duragesic patches can lead to the rapid release of the contents of the duragesic patch and absorption of a potentially fatal dose of fentanyl. Talk with your doctor and pharmacist to make sure it is safe to use duragesic fentanyl transdermal patch with all of your drugs. Duragesic patches come in four strengths, measured in microgramsperhour of fentanyl delivered.
This medicine is between 50 and 100 times more powerful than morphine, from which it is derived. While wearing a fentanyl patch, do not expose the site to heat from a heating pad, electric blanket, sauna, hot tub, heated waterbed, or excessive sun exposure, or hot climate. Side effects of duragesic fentanyl transdermal, warnings, uses. In this report, we describe a case of transbuccal and gastrointestinal ingestion of fentanyl patches and the management of such ingestion. Fentanyl accumulates to form a depot in the skin below the. Pharmacist lynn hostetler told cbs news that fentanyl, which is sold in a patch by orthomcneil under the brand name duragesic, is one of the most dangerous drugs he dispenses.
For example, heat can trigger a fentanyl overdose when using the pain patch. Health canada has announced that the makers of fentanyl transdermal patches are changing dosage guidelines in to reduce the risk. Fentanyl duragesic is a moderately priced drug used to treat chronic pain. Combining duragesic patches with other pain medications. You may bathe, swim, or shower while you are wearing a fentanyl patch. Fentanyl can cause serious unwanted effects or a fatal overdose if taken by children, pets, or adults who are not used to strong narcotic pain medicines. A strong prescription pain medicine that contains an opioid narcotic that is used to manage pain severe enough to require daily aroundtheclock, longterm treatment with an opioid, in people who are already regularly using opioid pain medicine, when other pain treatments such as nonopioid pain medicines or immediaterelease opioid medicines do not treat your. Reports of fentanyl abuse, including mixing fentanyl into heroin, have been reported more across the united states since 2015. Side effects may include profuse sweating, coughing, nausea, diarrhea, and tearing. See below for a comprehensive list of adverse effects. Along with its needed effects, a medicine may cause some unwanted effects. Do not use transdermal patches unless you have been regularly taking moderate to large amounts of narcotic pain medication. While wearing a fentanyl patch, do not expose the site to heat sources. Misuse of narcotic medicine can cause addiction, overdose, or death, especially in a child or other person using the medicine without a prescription.
Fentanyl transdermal duragesic side effects, medical. Fentanyl is not right for all types of pain, however. This document contains side effect information about fentanyl. Patients who are opioid tolerant are those receiving, for 1 week or longer, at least 60 mgday morphine, 25 mcgday transdermal fentanyl, 30 mgday po oxycodone, 8 mgday po hydromorphone, 25 mgday po oxymorphone, 60 mgday po hydrocodone, or an equianalgesic dose of another opioid. Legal fentanyl is taken as a lozenge or patch, or iv when used surgically. Fentanyl transdermal patch is available in a generic form and as the brandname drug duragesic. Duragesic is the most recognized brand name for fentanyl patches. After a duragesic patch has been applied, fentanyl passes into the skin a little at a time. Duragesic patches are a strong prescription pain medicine. The law firm of hissey kientz, llp is urging the manufacturers of the fentanyl or duragesic pain patches to address recurring problems with their products that could lead to a potentially fatal overdose. Aug 19, 2009 the law firm of hissey kientz, llp is urging the manufacturers of the fentanyl or duragesic pain patches to address recurring problems with their products that could lead to a potentially fatal overdose. Do not use a fentanyl patch that is cut, damaged, or changed in any way.
July 15, 2005 the fda today has issued a health advisory regarding the safe use of fentanyl skin patches brand name duragesic in response to reports of. The worst consequence of fentanyl toxicity is a fatal respiratory. Jan 09, 2018 16 dangers of fentanyl and the fentanyl patch. Learn about side effects, warnings, dosage, and more. Fentanyl patches durogesic for chronic pain nps medicinewise. Fentanyl, the pain medication inside the fentanyl patch, is an opioid. As a result of defects in the design, poor quality control and inadequate warnings, users could suffer fentanyl overdose resulting in a sudden death after putting the patch on their skin. Because of its high potency, patients who receive too much of the medication in the pain patch are at an increased risk of a fentanyl overdose. Fentanyl is available as a transdermal system for the treatment of chronic pain in opioidtolerant patients.
The product was designed to deliver ongoing pain management to patients. Use the patches exactly as directed to prevent serious side effects. Withdrawal symptoms, drug interactions, dosage, and pregnancy and breastfeeding safety are provided. Background information about duragesic and fentanyl. Duragesic patches because of seal breaches which might have allowed the medication to leak from the patch. If a medical professional did not advise you of the potential dangers of the fentanyl pain patch, as well as proper use of the medication, you may have a case. Duragesic transdermal patch 72 hour drug information, side. Up to a full day 24 hours may pass before the first dose begins to work. An overdose can cause severe breathing problems breathing may even stop, unconsciousness, and death.
Coming into accidental contact with the sticky side of the patch can cause the drug to be released into the bloodstream. Diet and weight loss digestive disorders drugs and supplements ear, nose, and. Fentanyl lawsuit duragesic generic pain patch impact law. Duragesic fentanyl transdermal system for transdermal administration is an opioid analgesic indicated for the management of pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm opioid treatment and for which alternative treatment options are inadequate. Duragesic fentanyl transdermal dosing, indications. The side effects of duragesic patch and fentanyl patch vary in severity. Highalert medications fentanyl patch consumer med safety. Diskospondylitis intervertebral disk infection in dogs and cats. Hissey kientz, llp warns duragesic patch users about. Duragesic patch and absorption of a potentially fatal dose of fentanyl. If you use cut or damaged patches, you may receive most or all of the medication at once, instead of slowly over 3 days. Because fentanyl is so powerful, even a small amount can be deadly. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions.
Some of the dosage forms listed on this page may not apply to the brand name duragesic. In february 2004, a leading fentanyl supplier, janssen pharmaceutica products, l. Using duragesic patches during pregnancy may cause lifethreatening withdrawal symptoms in the newborn. Using too much fentanyl skin patch, or taking too much of another narcotic with fentanyl skin patch, may cause an overdose. Duragesic or sublimaze is a narcotic opioid pain medication. Substitutes and alternatives to duragesic fentanyl for uses like cancer pain, pain after surgery and chronic pain. The patches are used to treat moderate to severe chronic pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm opioid treatment duragesic patches are used when other pain.
Generic fentanyl is covered by some medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The duragesic fentanyl patch is used to treat chronic pain by supplying a steady dose of fentanyl a powerful opioid pain medication over an extended period of timeusually up to 72 hours. Aug 05, 2016 legal fentanyl is taken as a lozenge or patch, or iv when used surgically. Aug 18, 2012 the duragesic fentanyl patch is used to treat chronic pain by supplying a steady dose of fentanyl a powerful opioid pain medication over an extended period of timeusually up to 72 hours. The chemical name is nphenyln12phenylethyl4piperidinyl propanamide. Side effects of duragesic fentanyl transdermal, warnings. Illegal fentanyl comes in many forms, in lethal doses, is sold illegally by criminals and taken illegally. Use of the fentanyl patch is known to cause a few serious, lifethreatening side effects, including. Fentanyl can slow or stop your breathing, and may be habitforming. Fentanyl transdermal patch duragesic is a prescription medication used to treat severe chronic pain such as cancer. Fentanyl also comes as a buccal and sublingual tablet, oral lozenge, sublingual spray.
Its available in many dosage forms, including a patch, injection, film, nasal spray, and lollipop. Severe weight loss and fentanyl analgesics pain killers. Transdermal drug delivery systems tdds, also known as medication patches, are becoming more popular with more than 25 transdermal medications available for a variety of indications. Although the drug can be injected or taken orally via a lollipop or lozenge, a common ingestion method is to take the drug transdermally through patches. The gel in the duragesic patch is made up of about 1% fentanyl, 23% ethanol, and 76% water. And thats even when the timereleased pain patch medication is prescribed properly. Dec, 2008 a number of patients have died after problems with the pain patch caused the gel inside to come in direct contact with their skin, says attorney michael hissey of hissey kientz, llp. Fentanyl transdermal duragesic side effects, medical uses. The patches are used to treat moderate to severe chronic pain in opioidtolerant patients, severe enough to require daily, aroundtheclock, longterm opioid treatment. Check with your doctor immediately if any of the following side effects occur. Fentanyl withdrawal symtoms fentanyl patch for withdrawal. Although not all of these side effects may occur, if they do occur they may need medical attention. Jan 28, 2020 bernstein kj, klausner ma potential dangers related to transdermal fentanyl duragesicr when used for postoperative pain. Fentanyl, also spelled fentanil, is an opioid used as a pain medication and together with other medications for anesthesia.
Fentanyl as duragesic comes in five strengths, which deliver fentanyl at different rates. Fda announces fentanyl duragesic patch recall youtube. Medically, fentanyl is used by injection, as a patch on the skin, as a nasal spray, or in the mouth. The duragesic fentanyl patch provides longterm pain relief and lowers the number of times you need to take pain medications each day. Fentanyl pain patch wrongful death lawsuit fentanyl.
The stronger the dose, the larger the patch, as more area of skin needs to be covered to ensure that more of the drug is being absorbed over the same period of time. The transdermal patch is a longacting formulation with a delayed onset of effect initially and a prolonged duration of action. To dispose of the duragesic patch, fold the patch in half with the sticky side inside. The duragesic patch contains fentanyl, an opioid and classed as a narcotic several times more potent than morphine. Raising your skinbody temperature, using cut or damaged fentanyl patches, or using the patch improperly such as by chewing it may cause fatal overdose. Duragesic durahgee zikfentanyl transdermalsystem, cii duragesic is. Duragesic label page 1 full prescribing information for. Also, avoid tight coverings over the patch and strenuous exercise, which can heat the body. Management of an oral ingestion of transdermal fentanyl. The risk for harm is higher if you use the wrong dosestrength, or if you use it. Fentanyl has a high risk for abuse and severe, possibly fatal, breathing problems. Avoid increasing your skin temperature atnear the application site by using products such as heating pads, electric blankets, hot tubs, heat lamps, or tanning lamps. Do not use transdermal patches unless you have been regularly using moderate to large amounts of opioid pain medication.
The duragesic skin patch should not be used if you need pain. Fentanyl is a synthetic opioid, meaning it is made in a laboratory but acts on the. Avoid drinking grapefruit juice or eating grapefruit while taking this medicine. The duragesic patch recalled again, fentanyl patients. Fentanyl transdermal route precautions mayo clinic. Duragesic patches are intended for transdermal use on intact skin only. Nov 05, 2019 duragesic is a skin patch containing fentanyl, an opioid pain medication. As someone in effective pain management, using a fentanyl patch, and being seen by a. Fentanyl is also used as a recreational drug, often mixed with heroin or cocaine. Chronic pain from hydrocodone to duragesic patch addiction. If a medical professional did not advise you of the potential dangers of the fentanyl pain patch. Fentanyl actiq side effects, dosage, interactions drugs.